So the interesting thing with the necrotic laboratory is the timing of your decision really matters here you'll want to solve the neural puzzle before even thinking about destroying anything. When you first enter look for the mind-archive interface which has this distinct glow pattern youll need to watch for the right moment to interact with it and purge the waking mind this gets you that permanent intelligence save advantage which is huge for later encounters

The lab itself has multiple interactive points but the key is finding your way to the locked section where the blade of oppressed souls waits its this really nice +1 longsword that deals bonus psychic damage, definitely worth grabbing before making any final decisions. The neural puzzle itself has specific patterns you need to match up, and if youre running a sage background character, youll get this cool brain blast inspiration moment

Maybe interesting is all the lore you can discover about the mind flayer plans and their grand design through various brain jar interactions like the fresh mind and true mind but timing is crucial here once you destroy the lab theres no going back. The good news is you dont lock yourself out of any major story stuff like the ketheric thorm confrontation, but youll definitely want to explore everything thoroughly before making that final choice about destroying it