When you want to maximize explosive damage, activate focus right before throwing to get that perfect aim window - the slow motion gives you crucial time to line up devastating hits. Keep an eye on enemy patterns, they typically bunch up for 2-3 seconds before spreading out again, which is your ideal moment to strike. Position yourself about 15-20 meters from the group, as this gives you the sweet spot for explosive radius while maintaining a safe distance.

For the real nasty encounters, time your focus cocktail use when you spot dense groups forming up, especially near choke points or abandoned vehicles. You'll notice freakers have this tendency to cluster tightly when approaching which is perfect for chain reactions. The attractor bomb combo works best by throwing the attractor first, waiting exactly 1.5 seconds for them to gather, then following up with explosives while focus is still active. Watch their movement patterns carefully, most groups will funnel through predictable paths letting you set up devastating combinations.

Really important detail about timing - after using focus your reload speed stays normal so try to have everything prepped beforehand. The explosive bolts are particularly nasty when you nail the timing, just remember theres about a quarter-second delay between impact and detonation so lead your shots accordingly. Maybe interesting but you can actually extend focus duration by triggering it right as enemies start their gathering animation giving you maximum crowd control potential.