Look around near acid anomalies for radio protection artifacts first, they spawn there pretty often and you'll want something like slug to counter the radiation from other artifacts you find. Always good to match protection levels - weak artifacts need weak protection, medium needs medium protection and so on. Keep anti-rad meds handy for emergencies, and vodka works in a pinch though it'll make you hungry pretty quick. The really important part is getting solid radiation-resistant gear from stashes, combining that with protective artifacts gives you way better coverage. Your echo device helps track down those anti-rad artifacts in anomaly fields, just take it slow and watch your radiation meter carefully. Something to remember - stacking multiple radioactive artifacts without matching protection is asking for trouble, especially in heavily contaminated areas. When you're geared up right with both artifacts and protective equipment, you can handle most radiation zones without burning through too many meds.