Missing content in your first run is absolutely normal and pretty much part of the core design. The world is massive with countless interconnected triggers, so tracking everything perfectly would be nearly impossible. Watch for specific timing windows when npcs appear - they often show up briefly in one spot before relocating somewhere else entirely. No quest markers means you'll need to really pay attention to dialogue cues and environmental hints to catch everything.

The most crucial thing to understand is the progression-sensitive nature of quests. Certain story beats will lock you out of content, especially after major boss victories or area transitions. A good example is how npcs react differently once you reach specific milestones, and some might vanish completely if you progress too far without meeting them. The recovery windows after these transitions are your best chance to catch up on missed content.

For the really hidden stuff, look for subtle environmental tells like suspicious walls or oddly placed items - these often indicate secret passages or upcoming npc spawns. The density of content means even experienced players discover new things on their fifth or sixth run, so don't stress about catching everything immediately. Your first playthrough is more about learning these systems than finding absolutely everything.}