Those persistent relic malfunctions can be quite frustrating because they're tied to some tricky mission triggers and dialogue sequences. Let me help you sort this out - there's actually a few different approaches depending on what you're working with.

For pc players, the most straightforward fix is grabbing either the fx begone or relicbegone mod (this works because these mods specifically target the visual effect system without breaking quest flags). Load your save with the mod active, make a fresh save, then you can actually remove the mod and keep the fix.

If you're on console or prefer staying mod-free, your best bet is completing brendan's questline over at megabuilding h8 in japantown, which is interesting because it ties into the game's deeper themes about ai consciousness. You'll want at least 6 in body to access these quests, and they're worth doing anyway since they provide some unique dialogue choices. Another solid option is pushing through panam's queen of the highway mission, which seems to reset some of the underlying status effects.

For temporary relief while you work on the bigger fixes, try to avoid skipping dialogue during key story beats, especially in missions like automatic love (this is where a lot of players accidentally trigger the permanent effect). If things get really bad, you can always reload a save from before the glitch started appearing, though i know that's not ideal. Just remember that normal relic malfunctions should only last about half a minute - anything longer is definitely a bug that needs addressing.

Something worth noting - if you've already finished brendan's stuff, trying either happy together or i fought the law can sometimes knock things back into place