Cutscene assassinations arent a thing in this game no matter what tools you've got. For eliminating generals, you need to handle it during actual gameplay when youre in control. Quick breakdown - poison and other tools work exclusively in active combat or stealth situations, not during story moments.

During important takedowns, youll need to actively use stealth mechanics, pull off combat moves, or set up environmental kills yourself. When targeting generals, focus on using actual gameplay mechanics like parry chains, smoke bombs, or kunai throws since cutscenes are just for watching the story unfold. Its worth noting that all major eliminations require your direct input, so plan your approach with the tools available during regular gameplay

Tip: smoke bombs combined with poison can be pretty effective when you need to take down heavily guarded targets during gameplay sequences